The Future of Research Communications and e-Scholarship

Genome-wide histone acetylation is altered in a transgenic mouse model of Huntington’s disease.

Authors: McFarland, Karen N Das, Sudeshna Sun, Ting Ting Leyfer, Dmitri Xia, Eva Sangrey, Gavin R Kuhn, Alexandre Luthi-Carter, Ruth Clark, Timothy W Sadri-Vakili, Ghazaleh Cha, Jang-Ho J In Huntington's disease (HD; MIM ID #143100), a fatal neurodegenerative disorder, transcriptional dysregulation is a key pathogenic feature. Histone modifications are altered in multiple cellular and animal … Read more

PAV ontology: Provenance, Authoring and Versioning

Authors: Paolo Ciccarese Stian Soiland-Reyes Khalid Belhajjame Alasdair J G Gray Carole Goble Tim Clark Provenance is a critical ingredient for establishing trust of published scientific content. This is true whether we are considering a data set, a computational workflow, a peer-reviewed publication or a simple scientific claim with supportive evidence. Existing vocabularies such as … Read more

Web Annotation as a First Class Object

Authors: Ciccarese, Paolo Soiland-Reyes, Stian Clark, Tim The W3C Open Annotation Data Model provides facilities for annotating content directly on the Web without changing the original content.Third-party semantic annotations of content are now emerging as first-class objects on the Web.   Journal: IEEE Internet Computing 2013 Archive: https://archive.force11.net/node/6385